Treatment of severe acne with low-dose isotretinoin.
نویسندگان
چکیده
1/M Acne conglobata 8 to 0 0.25 60.5 8.1 None None Elevated serum cholesterol, creatinine kinase at last visit, mild cheilitis 2/M Acne fulminans 8 to 2 0.18 55.5 10.0 Oral methylpred nisolone Adapalene gel Transient elevation of serum TG, mild cheilitis 3/F Acne fulminans 8 to 4 0.15 34.8 7.4 Oral prednisolone Clindamycin/ benzoyl-peroxide Transient elevation of serum cholesterol, γ-GT, TG, mild cheilitis 4/M Acne conglobata 8 to 2 0.16 112.3 16.2 Oral prednisolone Erythromycin cream Transient elevation of cholesterol, TG, alkaline phosphatase, mild cheilitis
منابع مشابه
Comparison of Low-Dose Treatment of Isotretinoin and Flutamide Combined with Oral Erythromycin for Female Patients with Severe Acne
Background & objectives: Acne is a chronic inflammation of pilosebaceous units and in severe form reflects a different response to treatment in an oral regime of antibiotics. The purpose of this study is to compare the effect of the combination of erythromycin and low dose oral isotretinoin with erythromycin and low dose flutamide in women suffering from severe acne. Methods: In a randomized co...
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Background: Few studies have investigated on vitamin D metabolites Serum levels, and calcium homeostasis in humans receiving retinoids, despite a substantial amount of literature concerning retinoid-induced osteoporosis in animals. We prospectively measured vitamin D metabolites serum levels and calcium homeostasis and radiographic bone changes in short course treatment with oral isotreti...
متن کاملCreatine phosphokinase values and myalgia during isotretinoin therapy
Background: Systemic isotretinoin is a very effective medication for the treatment of acne, but it has some side effects. One of its side effects is musculoskeletal problems such as increased levels of creatine phosphokinase (CPK), myalgia, and serious muscle damage such as rhabdomyolysis. The aim of this study was to evaluate the incidence of myalgia and its relationship with the elevation of ...
متن کاملA randomized comparative trial of two low-dose oral isotretinoin regimens in moderate to severe acne vulgaris
BACKGROUND Oral isotretinoin is highly effective in all forms and grades of acne, even in lower dosages (<0.5 mg/kg/day). There is a paucity of comparative data on the various low-dose regimens of oral isotretinoin in the Indian literature. OBJECTIVES To assess and compare the efficacy and tolerability of two low-dose oral isotretinoin treatment regimens (20 mg daily and 20 mg alternate days)...
متن کاملEffects of Isotretinoin on bone density and Calcium homeostasis in patients with Acne Vulgaris
Background and aim: Side effects of long-term systemic isotretinion use with high accumulative doses on skeletal system have been known, but there are few studies about the effects of short term isotretinoin therapy for acne patients. This study was aimed to recognize the effects of systemic isotretinion on calcium homeostasis and bone density in acne patients referring to clinics affilia...
متن کاملEvaluation of the efficacy of intermittent Isotretinoin doses in Acne patients
Background and objective: Oral isotretinoin is the only treatment that has an effect on all the major etiological factors involved in acne (Increased sebum production, alterations in microbial flora, hyperkeratinization of pilosebaceous duct, and inflammation). Considering complications and relative expense, several treatment regimens have been suggested. The objective of this study was to eval...
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ورودعنوان ژورنال:
- Acta dermato-venereologica
دوره 92 3 شماره
صفحات -
تاریخ انتشار 2012